Tomoharu Osada: search on Z-Library

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1

Production of inbred and hybrid transgenic mice carrying large (> 200 kb) foreign DNA fragments by intracytoplasmic sperm injection

Tomoharu Osada, Atsushi Toyoda, Stefan Moisyadi, Hidenori Akutsu, Masahira Hattori, Yoshiyuki Sakaki, Ryuzo Yanagimachi

Journal:

Molecular Reproduction and Development

Year:

2005

Language:

english

File:

PDF, 254 KB

english, 2005

2

Repolarization studies using human stem cell-derived cardiomyocytes: Validation studies and best practice recommendations

Gintant, Gary, Kaushik, Emily Pfeiffer, Feaster, Tromondae, Stoelzle-Feix, Sonja, Kanda, Yasunari, Osada, Tomoharu, Smith, Godfrey, Czysz, Katherine, Kettenhofen, Ralf, Lu, Hua Rong, Cai, Beibei, Shi,

Journal:

Regulatory Toxicology and Pharmacology

Year:

2020

File:

PDF, 2.29 MB

2020

3

Rapid and enhanced repolarization in sandwich-cultured hepatocytes on an oxygen-permeable membrane

Hitoshi Matsui, Tomoharu Osada, Yasuyuki Moroshita, Masaru Sekijima, Teruo Fujii, Shoji Takeuchi, Yasuyuki Sakai

Journal:

Biochemical Engineering Journal

Year:

2010

Language:

english

File:

PDF, 1.28 MB

english, 2010

4

Male Reproductive Defects Caused by Puromycin-Sensitive Aminopeptidase Deficiency in Mice

Osada, Tomoharu, Watanabe, Gen, Kondo, Shunzo, Toyoda, Masashi, Sakaki, Yoshiyuki, Takeuchi, Takashi

Journal:

Molecular Endocrinology

Year:

2001

Language:

english

File:

PDF, 1.33 MB

english, 2001

5

Mouse Embryos and Chimera Cloned from Neural Cells in the Postnatal Cerebral Cortex

Makino, Hatsune, Yamazaki, Yukiko, Hirabayashi, Takahiro, Kaneko, Ryosuke, Hamada, Shun, Kawamura, Yoshimi, Osada, Tomoharu, Yanagimachi, Ryuzo, Yagi, Takeshi

Journal:

Cloning & Stem Cells

Year:

2005

Language:

english

File:

PDF, 2.85 MB

english, 2005

6

Field potential measurement using iPS cell-derived cardiomyocytes for the prediction of cardiotoxicity in vitro

Sakakibara, Mototsugu, Kitamura, Tetsuo, Otsuki, Makoto, Bunai, Fumihide, Minami, Daisuke, Fujisaki, Yukiko, Sekijima, Masaru, Osada, Tomoharu

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2014

Language:

english

File:

PDF, 73 KB

english, 2014

7

Drug-Induced Torsadogenic Risk Prediction Using Human iPS Cell-Derived Cardiomyocytes and MEA System (I)

Ando, Hiroyuki, Yoshinaga, Takashi, Yamamoto, Wataru, Asakura, Keiichi, Taniguchi, Tomohiko, Ojima, Atsuko, Uda, Takaaki, Shinkyo, Raku, Kikuchi, Kiyomi, Osada, Tomoharu, Hayashi, Seiji, Kasai, Chieko

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2017

File:

PDF, 2 KB

2017

8

PolyADP-Ribosylation Is Required for Pronuclear Fusion during Postfertilization in Mice

Osada, Tomoharu, Ogino, Hideki, Hino, Toshiaki, Ichinose, Sachiyo, Nakamura, Kenji, Omori, Akira, Noce, Toshiaki, Masutani, Mitsuko, Wang, Hongmei

Journal:

Year:

2010

Language:

english

File:

PDF, 2.59 MB

english, 2010

9

A new paradigm for drug-induced torsadogenic risk assessment using human iPS cell-derived cardiomyocytes

Ando, Hiroyuki, Yoshinaga, Takashi, Yamamoto, Wataru, Asakura, Keiichi, Uda, Takaaki, Taniguchi, Tomohiko, Ojima, Atsuko, Shinkyo, Raku, Kikuchi, Kiyomi, Osada, Tomoharu, Hayashi, Seiji, Kasai, Chieko

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2017

Language:

english

File:

PDF, 1.98 MB

english, 2017

10

Drug-Induced Torsadogenic Risk Prediction Using Human iPS Cell-Derived Cardiomyocytes and MEA System (II)

Yoshinaga, Takashi, Ando, Hiroyuki, Taniguchi, Tomohiko, Uda, Takaaki, Yamamoto, Wataru, Asakura, Keiichi, Ojima, Atsuko, Shinkyo, Raku, Kikuchi, Kiyomi, Osada, Tomoharu, Hayashi, Seiji, Kasai, Chieko

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2017

Language:

english

File:

PDF, 54 KB

english, 2017

11

Availability of recording field potential of human stem cell-derived cardiomyocytes by multi-electrode array system

Mototsugu Sakakibara, Mikiko Koike, Tetsuo Kitamura, Minoru Tateno, Tomoharu Osada, Fumimasa Nomura, Tomoyuki Kaneko, Masaru Sekijima, Kenji Yasuda

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2011

Language:

english

File:

PDF, 57 KB

english, 2011

12

Neuronal Genomics Using Mouse Cloning with the Single Neuronal Nucleus

Osada, Tomoharu, Yagi, Takeshi

Journal:

Current Genomics

Year:

2006

Language:

english

File:

PDF, 463 KB

english, 2006

13

Enhanced bile canaliculi formation enabling direct recovery of biliary metabolites of hepatocytes in 3D collagen gel microcavities

Matsui, Hitoshi, Takeuchi, Shoji, Osada, Tomoharu, Fujii, Teruo, Sakai, Yasuyuki

Journal:

Year:

2012

Language:

english

File:

PDF, 679 KB

english, 2012

14

Trial for data analysis of drug responses in primary rodent neurons and human-induced pluripotent stem cell-derived neurons using MEA and deep learning

Miyamoto, Norimasa, Ojima, Atsuko, Kitamura, Tetsuo, Osada, Tomoharu, Kadowaki, Tadashi, Yoshinaga, Takashi

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2018

Language:

english

File:

PDF, 62 KB

english, 2018

15

Puromycin-Sensitive Aminopeptidase Gene (Psa) Maps to Mouse Chromosome 11

Tomoharu Osada, Yoshiyuki Sakaki, Takashi Takeuchi

Journal:

Year:

1999

Language:

english

File:

PDF, 45 KB

english, 1999

16

Poly(ADP-ribosylation) regulates chromatin organization through histone H3 modification and DNA methylation of the first cell cycle of mouse embryos

Osada, Tomoharu, Rydén, Anna-Margareta, Masutani, Mitsuko

Journal:

Biochemical and Biophysical Research Communications

Year:

2013

Language:

english

File:

PDF, 1.30 MB

english, 2013

17

Improvement of acquisition and analysis methods in multi-electrode array experiments with iPS cell-derived cardiomyocytes

Asakura, Keiichi, Hayashi, Seiji, Ojima, Atsuko, Taniguchi, Tomohiko, Miyamoto, Norimasa, Nakamori, Chiaki, Nagasawa, Chiho, Kitamura, Tetsuo, Osada, Tomoharu, Honda, Yayoi, Kasai, Chieko, Ando, Hiroy

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2015

Language:

english

File:

PDF, 2.21 MB

english, 2015

18

Electrophysiological and Pharmacological Characterization of Human iPS Cell-Derived Cardiomyocytes As a Model for Predicting the Drug-Induced Arrhythmic Events in Human Hearts

Yamamoto, Wataru, Asakura, Keiichi, Ando, Hiroyuki, Taniguchi, Tomohiko, Ojima, Atsuko, Uda, Takaaki, Osada, Tomoharu, Hayashi, Seiji, Kasai, Chieko, Miyamoto, Norimasa, Tashibu, Hiroyuki, Yoshinaga,

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2017

Language:

english

File:

PDF, 81 KB

english, 2017

19

Pacing of Human iPS Cell-Derived Cardiomyocytes (hiPSC-CMs) is Effective for Detecting Chronic Arrhythmogenic Risk of Pharmaceutical Compounds

Osada, Tomoharu, Kitamura, Tetsuo, Yoshikawa, Kimihito, Bunai, Fumihide, Obo, Mayumi, Uchida, Hideomi, Onishi, Yasuyuki, Hiratsuka, Hideaki, Inoue, Hiroaki

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2017

Language:

english

File:

PDF, 70 KB

english, 2017

20

Isolation of New Protein Phosphatase Inhibitors from Two Cyanobacteria Species, Planktothrix spp.

Sano, Tomoharu, Usui, Takeo, Ueda, Kazunori, Osada, Hiroyuki, Kaya, Kunimitsu

Journal:

Journal of Natural Products

Year:

2001

Language:

english

File:

PDF, 99 KB

english, 2001

21

Synthesis and biological activities of reveromycin A and spirofungin A derivatives

Takeshi Shimizu, Takeo Usui, Makoto Fujikura, Makoto Kawatani, Tomoharu Satoh, Kiyotaka Machida, Naoki Kanoh, Je-Tae Woo, Hiroyuki Osada, Mikiko Sodeoka

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 206 KB

english, 2008

22

Puromycin-Sensitive Aminopeptidase Is Essential for the Maternal Recognition of Pregnancy in Mice

Osada, Tomoharu, Watanabe, Gen, Sakaki, Yoshiyuki, Takeuchi, Takashi

Journal:

Molecular Endocrinology

Year:

2001

Language:

english

File:

PDF, 1.46 MB

english, 2001

23

Electrophysiological Characteristics of Human iPSC-Derived Cardiomyocytes for the Assessment of Drug-Induced Proarrhythmic Potential

Yamamoto, Wataru, Asakura, Keiichi, Ando, Hiroyuki, Taniguchi, Tomohiko, Ojima, Atsuko, Uda, Takaaki, Osada, Tomoharu, Hayashi, Seiji, Kasai, Chieko, Miyamoto, Norimasa, Tashibu, Hiroyuki, Yoshinaga,

Journal:

Year:

2016

Language:

english

File:

PDF, 1.50 MB

english, 2016

24

The importance of physiological oxygen concentrations in the sandwich cultures of rat hepatocytes on gas-permeable membranes

Xiao, Wenjin, Shinohara, Marie, Komori, Kikuo, Sakai, Yasuyuki, Matsui, Hitoshi, Osada, Tomoharu

Journal:

Biotechnology Progress

Year:

2014

Language:

english

File:

PDF, 838 KB

english, 2014

25

Development of torsadogenic risk assessment using human induced pluripotent stem cell-derived cardiomyocytes: Japan iPS Cardiac Safety Assessment (JiCSA) update

Kanda, Yasunari, Yamazaki, Daiju, Osada, Tomoharu, Yoshinaga, Takashi, Sawada, Kohei

Journal:

Journal of Pharmacological Sciences

Year:

2018

Language:

english

File:

PDF, 726 KB

english, 2018

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